Osteoarthritis-Osteoarthritis - Symptoms & causes - Mayo Clinic (2024)

Overview

Osteoarthritis is the most common form of arthritis, affecting millions of people worldwide. It occurs when the protective cartilage that cushions the ends of the bones wears down over time.

Although osteoarthritis can damage any joint, the disorder most commonly affects joints in your hands, knees, hips and spine.

Osteoarthritis symptoms can usually be managed, although the damage to joints can't be reversed. Staying active, maintaining a healthy weight and receiving certain treatments might slow progression of the disease and help improve pain and joint function.

Symptoms

Osteoarthritis symptoms often develop slowly and worsen over time. Signs and symptoms of osteoarthritis include:

  • Pain. Affected joints might hurt during or after movement.
  • Stiffness. Joint stiffness might be most noticeable upon awakening or after being inactive.
  • Tenderness. Your joint might feel tender when you apply light pressure to or near it.
  • Loss of flexibility. You might not be able to move your joint through its full range of motion.
  • Grating sensation. You might feel a grating sensation when you use the joint, and you might hear popping or crackling.
  • Bone spurs. These extra bits of bone, which feel like hard lumps, can form around the affected joint.
  • Swelling. This might be caused by soft tissue inflammation around the joint.

Osteoarthritis-Osteoarthritis - Symptoms & causes - Mayo Clinic (1)

Bone spurs on spine

In osteoarthritis of the spine, disks narrow and bone spurs form.

Osteoarthritis-Osteoarthritis - Symptoms & causes - Mayo Clinic (2)

Osteoarthritis of the hip

The hip joint shown on the left side of the image is normal, but the hip joint shown on the right side of the image shows deterioration of cartilage and the formation of bone spurs due to osteoarthritis.

When to see a doctor

If you have joint pain or stiffness that doesn't go away, make an appointment with your doctor.

Request an appointment

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Causes

Osteoarthritis occurs when the cartilage that cushions the ends of bones in your joints gradually deteriorates. Cartilage is a firm, slippery tissue that enables nearly frictionless joint motion.

Eventually, if the cartilage wears down completely, bone will rub on bone.

Osteoarthritis has often been referred to as a wear and tear disease. But besides the breakdown of cartilage, osteoarthritis affects the entire joint. It causes changes in the bone and deterioration of the connective tissues that hold the joint together and attach muscle to bone. It also causes inflammation of the joint lining.

Risk factors

Factors that can increase your risk of osteoarthritis include:

  • Older age. The risk of osteoarthritis increases with age.
  • Sex. Women are more likely to develop osteoarthritis, though it isn't clear why.
  • Obesity. Carrying extra body weight contributes to osteoarthritis in several ways, and the more you weigh, the greater your risk. Increased weight adds stress to weight-bearing joints, such as your hips and knees. Also, fat tissue produces proteins that can cause harmful inflammation in and around your joints.
  • Joint injuries. Injuries, such as those that occur when playing sports or from an accident, can increase the risk of osteoarthritis. Even injuries that occurred many years ago and seemingly healed can increase your risk of osteoarthritis.
  • Repeated stress on the joint. If your job or a sport you play places repetitive stress on a joint, that joint might eventually develop osteoarthritis.
  • Genetics. Some people inherit a tendency to develop osteoarthritis.
  • Bone deformities. Some people are born with malformed joints or defective cartilage.
  • Certain metabolic diseases. These include diabetes and a condition in which your body has too much iron (hemochromatosis).

Complications

Osteoarthritis is a degenerative disease that worsens over time, often resulting in chronic pain. Joint pain and stiffness can become severe enough to make daily tasks difficult.

Depression and sleep disturbances can result from the pain and disability of osteoarthritis.

Osteoarthritis-Osteoarthritis - Symptoms & causes - Mayo Clinic (2024)

FAQs

Osteoarthritis-Osteoarthritis - Symptoms & causes - Mayo Clinic? ›

Primary osteoarthritis has no known cause. Secondary osteoarthritis is caused by another disease, infection, injury, or deformity. Osteoarthritis starts with the breakdown of cartilage in the joint. As the cartilage wears down, the bone ends may thicken and form bony growths (spurs).

What is the root cause of osteoarthritis? ›

Primary osteoarthritis has no known cause. Secondary osteoarthritis is caused by another disease, infection, injury, or deformity. Osteoarthritis starts with the breakdown of cartilage in the joint. As the cartilage wears down, the bone ends may thicken and form bony growths (spurs).

What triggers osteoarthritis? ›

Cause of Osteoarthritis

Osteoarthritis happens when the cartilage and other tissues within the joint break down or have a change in their structure. This does not happen because of simple wear and tear on the joints. Instead, changes in the tissue can trigger the breakdown, which usually happens gradually over time.

What is the best vitamin for osteoarthritis? ›

Several nutritional supplements have shown promise for relieving pain, stiffness and other arthritis symptoms. Glucosamine and chondroitin, omega-3 fatty acids, SAM-e and curcumin are just some of the natural products researchers have studied for osteoarthritis (OA) and rheumatoid arthritis (RA).

What are 5 symptoms of osteoarthritis? ›

The most common symptoms of osteoarthritis include:
  • Pain in a joint (especially when you're moving it).
  • Stiffness.
  • Swelling near a joint.
  • A decreased range of motion (how far you can move a joint).
  • Feeling like a joint isn't as strong or stable as it usually is.
Oct 2, 2023

How do you stop osteoarthritis from progressing? ›

The Bottom Line. Ultimately, the best defense against any disease, including OA, is a healthy lifestyle. Diet, exercise, sleep, managing stress and whether you smoke, or drink can have a tremendous influence on overall health, and the health of your joints.

Which foods aggravate osteoarthritis? ›

5 Foods to Avoid
  • Red meat and fried foods. Fried foods and red meat contain high levels of advanced glycation end products (AGEs), which are known for stimulating inflammation. ...
  • Sugars. ...
  • Dairy. ...
  • Refined carbohydrates. ...
  • Alcohol and tobacco.
Dec 21, 2020

What should you not do with osteoarthritis? ›

Five Everyday Activities to Avoid With Osteoarthritis
  • Running on uneven surfaces. It's important to avoid running or working out on uneven surfaces. ...
  • High-impact sports. ...
  • Repetitive motions. ...
  • Lifting heavy objects. ...
  • Wearing high heels.
Mar 25, 2022

What makes osteoarthritis worse? ›

Some reasons that symptoms might worsen include: overdoing an activity or carrying out repetitive motions. trauma to the joint. the development of bone spurs.

What is the best painkiller for osteoarthritis? ›

Pain relief medicines
  • Paracetamol. If you have pain caused by osteroarthritis, your GP might suggest you consider taking paracetamol for short-term pain relief. ...
  • Non-steroidal anti-inflammatory drugs (NSAIDs) A GP may prescribe a non-steroidal anti-inflammatory drug (NSAID). ...
  • Opioids. ...
  • Capsaicin cream. ...
  • Steroid injections.

What is the strongest natural anti-inflammatory? ›

  1. Omega-3 fatty acids. Omega-3 fatty acids , which are abundant in fatty fish such as salmon or tuna, are among the most potent anti-inflammatory supplements. ...
  2. Curcumin. ...
  3. S-adenosylmethionine. ...
  4. Zinc. ...
  5. Green tea. ...
  6. Frankincense. ...
  7. Capsaicin. ...
  8. Cat's claw.

What hurts when you have osteoarthritis? ›

Osteoarthritis is the most common form of arthritis, affecting millions of people worldwide. It occurs when the protective cartilage that cushions the ends of the bones wears down over time. Although osteoarthritis can damage any joint, the disorder most commonly affects joints in your hands, knees, hips and spine.

What is the newest treatment for osteoarthritis? ›

A new drug called talarozole may help boost levels of retinoic acid in the body. Retinoic acid has been shown to suppress inflammation and joint cartilage damage caused by osteoarthritis. Osteoarthritis — a painful condition leading to joint pain, stiffness, and swelling — impacts 32 million US adults.

Can you reverse osteoarthritis? ›

Osteoarthritis symptoms can usually be managed, although the damage to joints can't be reversed.

What is the best pain relief for osteoarthritis? ›

Nonsteroidal anti-inflammatory drugs (NSAIDs).

Over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve), taken at the recommended doses, typically relieve osteoarthritis pain. Stronger NSAIDs are available by prescription.

What is the most effective treatment for osteoarthritis? ›

Exercise. Exercise is one of the most important treatments for people with osteoarthritis, whatever your age or level of fitness. Your physical activity should include a combination of exercises to strengthen your muscles and exercises to improve your general fitness.

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